Authors (including presenting author) :
Chiu WY, Fung SL, Fong KS, Chau SY, Law YY, Chung CY, Cheung HW, Poon YMA
Affiliation :
Department of Medicine and Therapeutics, Prince of Wales Hospital
Introduction :
Coronary angiography(CA) and percutaneous coronary intervention(PCI) are critical procedures for managing coronary artery disease(CAD), traditionally requiring fast after midnight in general. Recent evidence suggests that prolonged fasting may lead to adverse effects, such as dehydration, hypoglycemia, and increased postoperative complications. This study investigates the feasibility and safety of shortened fasting duration, aiming to enhance patient comfort and clinical outcomes.
Objectives :
The primary objective of this prospective, randomized controlled trial was to evaluate the impact of modified fasting protocols on patient satisfaction, metabolic stability, and clinical outcomes among patients undergoing CA and PCI.
Methodology :
A total of 400 participants were assigned to either an intervention group, adhering to updated fasting guidelines (eight hours for solid foods, six hours for non-fatty solids, and two hours for clear liquids), or a control group, following traditional fasting practices. Data collection included fasting duration, clinical outcomes (creatinine and glucose levels), and patient satisfaction assessed through questionnaires.
Result & Outcome :
The intervention group exhibited significantly reduced fasting duration: an average of 12.083 hours for solid food and 5.50 hours for liquids, compared to 14.166 hours and 6.33 hours in the control group, respectively (p < 0.05). Clinical outcomes showed improved renal function in the intervention group, with lower post-procedural creatinine levels (p = 0.0125) and stable blood glucose levels across both groups. Patient satisfaction was notably higher in the intervention group, indicating a positive response to the revised fasting protocols.
