Stereotactic function neurosurgery has been evolving with the milestone development in radiology. From X-ray stereotactic intracranial localization, neurosurgeons have been using a head-frame to target the deep brain for lesions. With the invention of CT and MRI imaging, Neurosurgeons can proceed with sophisticate deep brain localization in precision, within 1mm in accuracy, with a head frame. Deep brain stimulation is the trailblazer in the discovery of deep brain function and therapy for movement disorders, ie Parkinson's disease. The challenges of achieving high precision together with patient comfort, ie discomfort by the head frame, is mounting. The development of intra-operative MRI imaging is riding on this challenge. Teams in hospital authority are seizing the opportunity, the era of intra-operative MRI, to tackle this challenge.